| Hazard Information | Back Directory | [Description]
TAMRA-Azide-PEG-Biotin is a TAMRA dye biotin reagent containing a biotin group and an azide group, which enables Click Chemistry-mediated labeling of alkyne-tagged proteins. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
TAMRA-Azide-PEG-biotin is a dye derivative of TAMRA (HY-135640). TAMRA-Azide-PEG-biotin contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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