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1798-50-1

1798-50-1 Structure

1798-50-1 Structure
IdentificationMore
[Name]

Diphenylpiperidin-4-ylmethanol hydrochloride
[CAS]

1798-50-1
[Synonyms]

ALPHA,ALPHA-DIPHENYL-4-PIPERIDINOMETHANOL, HYDROCHLORIDE
AZACYCLONOL HYDROCHLORIDE
DIPHENYL-PIPERIDIN-4-YL-METHANOLHYDROCHLORIDE
alpha-(4-piperidyl)benzhydrolhydrochloride
alpha,alpha-diphenyl-4-piperidinemethanohydrochloride
alpha,alpha-diphenyl-4-piperidinemethanolhydrochloride
frenquelhydrochloride
gamma-pipradolhydrochloride
alpha,alpha-diphenylpiperidine-4-methanol hydrochloride
AZACYCLONO HYDROCHLORIDE
ALPHA,ALPHA-DIPHENYL-4-PIPERIDINOMETHANOL HCL
AZACYCLONOL HCL
Azacylononl
A:acyclonol hydrochloride
[EINECS(EC#)]

217-284-9
[Molecular Formula]

C18H22ClNO
[MDL Number]

MFCD00039039
[Molecular Weight]

303.83
[MOL File]

1798-50-1.mol
Chemical PropertiesBack Directory
[Appearance]

white to off-white crystalline powder
[Melting point ]

270-281 °C
[form ]

Crystalline Powder
[color ]

White to off-white
[CAS DataBase Reference]

1798-50-1(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
[REACH Registrations]

Active
[HazardClass ]

IRRITANT
[HS Code ]

29333999
Hazard InformationBack Directory
[Chemical Properties]

white to off-white crystalline powder
[Originator]

Frenquel,Merrell,US,1955
[Manufacturing Process]

A mixture of 26 g (0.1 mol) of α-(4-pyridyl)-benzhydrol, 1.5 g of platinum oxide, and 250 ml of glacial acetic acid is shaken at 50-60°C under hydrogen at a pressure of 40-50 lb/in2. The hydrogenation is complete in 2 to 3 hours. The solution is filtered and the filtrate evaprated under reduced pressure. The residue is dissolved in a mixture of equal parts of methanol and butanone and 0.1 mol of concentrated hydrochloric acid is added. The mixture is cooled and filtered to give about 30 g of α-(4-piperidyl)benzhydrol hydrochloride, MP 283- 285°C, as a white, crystalline substance.
The free base is readily obtained from the hydrochloride salt by treatment with ammonia and when so obtained has a melting point of 160-161°C.
[Brand name]

Frenquel (Marion Merrell Dow).
[Therapeutic Function]

Tranquilizer
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

alpha,alpha-Diphenyl-4-piperidinomethanol hydrochloride, 98%(1798-50-1)
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