| Identification | Back Directory | [Name]
RORγt Inverse agonist 2 | [CAS]
1801197-92-1 | [Synonyms]
RORγt Inverse agonist 2
Cyclohexanecarboxylic acid, 4-[[(3R)-3-[(4-fluorophenyl)sulfonyl]-3-[4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]-1-pyrrolidinyl]carbonyl]-, trans- | [Molecular Formula]
C27H25F8NO5S | [MDL Number]
MFCD31813912 | [MOL File]
1801197-92-1.mol | [Molecular Weight]
627.54 |
| Hazard Information | Back Directory | [Uses]
RORγt Inverse agonist 2 is a selective, orally active RORγt inverse agonist with an EC50 of 119 nM[1]. | [References]
[1] Duan JJ, et al. Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists. ACS Med Chem Lett. 2019 Feb 26;10(3):367-373. DOI:10.1021/acsmedchemlett.9b00010 |
|
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
|