ChemicalBook--->CAS DataBase List--->1802497-05-7

1802497-05-7

1802497-05-7 Structure

1802497-05-7 Structure
IdentificationBack Directory
[Name]

Terrelumamide A
[CAS]

1802497-05-7
[Synonyms]

Terrelumamide A
Terrelulamide A
[Molecular Formula]

C20H20N6O7
[MOL File]

1802497-05-7.mol
[Molecular Weight]

456.41
Chemical PropertiesBack Directory
[density ]

1.473±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

A solid
[pka]

8.00±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Terrelumamide A is a lumazine-containing peptide. Terrelumamide A is isolated from the culture broth of the marine-derived fungus Aspergillus terreus. Terrelumamide A exhibits pharmacological activity by improving insulin sensitivity. Terrelumamide A has the potential in the application of DNA sequence recognition[1].
[Biological Activity]

Terrelumamide A is a lumazine-containing peptide fungal metabolite originally isolated from A. terreus.1 It increases adiponectin production, a marker of insulin sensitivity, in human bone marrow mesenchymal stem cells (hBM-MSCs; EC50 = 37.1 μM).
[storage]

Store at -20°C
[References]

|1. You, M., Liao, L., Hong, S.H., et al. Lumazine peptides from the marine-derived fungus Aspergillus terreus. Mar. Drugs 13(3), 1290-1303 (2015).
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