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1807501-83-2

1807501-83-2 Structure

1807501-83-2 Structure
IdentificationBack Directory
[Name]

endo-BCN-PEG4-t-butyl ester
[CAS]

1807501-83-2
[Synonyms]

endo-BCN-PEG4-Boc
endo-BCN-PEG4-CH2CH2COOtBu
endo-BCN-PEG4-t-butyl ester
[Molecular Formula]

C26H43NO8
[MDL Number]

MFCD28505580
[MOL File]

1807501-83-2.mol
[Molecular Weight]

497.62
Chemical PropertiesBack Directory
[Boiling point ]

594.3±45.0 °C(Predicted)
[density ]

1.13±0.1 g/cm3(Predicted)
[solubility ]

Soluble in DMSO, DCM, DMF
[pka]

12.05±0.46(Predicted)
Hazard InformationBack Directory
[Description]

endo-BCN-PEG4-t-butyl ester is a click chemistry linker containing a BCN group and a t-butyl protected carboxyl group. The BCN group can react with azide-tagged molecules. The protected carboxyl group (COOH) prevents self coupling or polymerization under standard acid/amine or acid/hydroxyl coupling conditions. The t-butyl ester can be converted to free acid under acidc condition.
[Uses]

endo-BCN-PEG4-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
[IC 50]

PEGs; Alkyl/ether
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