ChemicalBook--->CAS DataBase List--->1881221-47-1

1881221-47-1

Request For Quotation
1881221-47-1 Structure

1881221-47-1 Structure
IdentificationBack Directory
[Name]

-
[CAS]

1881221-47-1
[Synonyms]

BCN-PEG4-acid
BCN-endo-PEG4-COOH
BCN-PEG4-ACID (ENDO)
[Molecular Formula]

C22H35NO8
[MOL File]

1881221-47-1.mol
[Molecular Weight]

441.52
Chemical PropertiesBack Directory
[Boiling point ]

608.2±55.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
[storage temp. ]

Storage temp. 2-8°C
[form ]

Viscous Liquid
[pka]

4.28±0.10(Predicted)
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501
Hazard InformationBack Directory
[Uses]

endo-BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. endo-BCN-PEG4-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
[IC 50]

Cleavable Linker
[References]

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
1881221-47-1 suppliers list
Company Name: Henan Mengtai Pharmaceutical Technology Co., Ltd  Gold
Telephone: 17634413542
Website: mengtaichem.com
Company Name: Borenpharm Co., Ltd  
Telephone: 027-65563561 13026317987;
Website: http://www.borenpharm.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Telephone: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Changzhou Hopschain Chemical Co.,Ltd.  
Telephone: 85528066 13775048983
Website: http://www.hopschem.cn
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
Telephone: +86-156-80926068 +86-15680926068
Website: http://www.confluore.cn/
Company Name: Zhengzhou Acme Chemical Co., Ltd.  
Telephone: 037163312495 13303845143
Website: www.acmechem.cn
Company Name: Hangzhou Huarong Pharm Co., Ltd.  
Telephone: 571-86758373 +8613588754946
Website: https://www.huarongpharm.com/
Company Name: Changsha Bono New Materials Technology Co., Ltd.  
Telephone: 18191076804
Website: www.bonosci.com
Company Name: Shanghai Minhan Pharmaceutical Technology Co., Ltd.  
Telephone: 17612188245
Website: http://www.suppliers.integle.com
Company Name: JW & Y Pharmlab Co., Ltd.  
Telephone: 021-64340559 13651849907
Website: http://www.jwypharmlab.com.cn
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Telephone: 13675144456
Website: http://www.synzest.com
Company Name: anqing sinosynth new materials technology co,ltd  
Telephone: 18055625120
Website: www.chemicalbook.com/ShowSupplierProductsList691621/0_EN.htm
Company Name: Shanghai Haohong Pharmaceutical Co., Ltd.  
Telephone: 400-8210725 4008210725
Website: https://www.leyan.com/
Company Name: Affinity（Wuhan）Ltd.  
Telephone: 15841022315
Website: https://precisepeg.com
Company Name: Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd  
Telephone: 0431-80514535 19917294565
Website: www.chemextension.com
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
Company Name: Vicbio Biotechnology Co., Ltd.  
Telephone: 13621190864 13691409741
Website: www.vicbio.com/
Company Name: Beijing Solarbio Science & Tecnology Co., Ltd.  
Telephone: 010-50973130 17801761073
Website: www.solarbio.com/
Tags:1881221-47-1 Related Product Information
1993134-72-7 1807501-85-4 2226472-38-2 1807501-83-2 1807501-82-1 2126805-02-3