| Identification | Back Directory | [Name]
Benz[7,8]indolizino[3,2-c]quinolin-6(5H)-one, 3,11-dihydroxy-14-(3-hydroxy-4-methoxyphenyl)-2,12-dimethoxy- | [CAS]
1809535-57-6 | [Synonyms]
Benz[7,8]indolizino[3,2-c]quinolin-6(5H)-one, 3,11-dihydroxy-14-(3-hydroxy-4-methoxyphenyl)-2,12-dimethoxy- | [Molecular Formula]
C28H22N2O7 | [MOL File]
1809535-57-6.mol | [Molecular Weight]
498.48 |
| Hazard Information | Back Directory | [Uses]
Azalamellarin N is an inhibitor of pyroptosis and has different inhibitory effects on different pyroptosis inducers. Azalamellarin N inhibits pyroptosis by targeting molecules that act upstream of NLRP3 inflammasome activation, rather than directly targeting components of the NLRP3 inflammasome. Inhibitory potency against different pyroptosis inducers: Nigericin (HY-127019) > R837 (HY-B0180)[1]. | [References]
[1] Takouda J, et al. Identification of Azalamellarin N as a Pyroptosis Inhibitor. Biol Pharm Bull. 2024;47(1):28-36. DOI:10.1248/bpb.b23-00569 |
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