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1810726-08-9

1810726-08-9 Structure

1810726-08-9 Structure
IdentificationBack Directory
[Name]

Polygodial pyridazine
[CAS]

1810726-08-9
[Synonyms]

Polygodial pyridazine
[Molecular Formula]

C15H22N2
[MOL File]

1810726-08-9.mol
[Molecular Weight]

230.35
Chemical PropertiesBack Directory
[Boiling point ]

357.2±11.0 °C(Predicted)
[density ]

1.010±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

A solid
[pka]

4.20±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

Polygodial pyridazine (compound 7) is a polygodial analogue and a TRPV1 agonist with a GI50 of 72 μM against MCF-7. Polygodial pyridazine can be utilized in cancer research[1].
[IC 50]

TRPV1
[References]

[1] Dasari R, et al. Synthetic and Biological Studies of Sesquiterpene Polygodial: Activity of 9-Epipolygodial against Drug-Resistant Cancer Cells. ChemMedChem. 2015 Dec;10(12):2014-26. DOI:10.1002/cmdc.201500360
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