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182410-73-7

182410-73-7 Structure

182410-73-7 Structure
IdentificationBack Directory
[Name]

(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate
[CAS]

182410-73-7
[Synonyms]

D-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester
(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate
[Molecular Formula]

C28H24N2O6
[MOL File]

182410-73-7.mol
[Molecular Weight]

484.5
Chemical PropertiesBack Directory
[density ]

1.39±0.1 g/cm3(Predicted)
[pka]

10.14±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

Fmoc-(D-Phe)-Osu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

Cleavable Linker
[References]

[1] Geoffrey C. Winters, et al. Sulfonamide-containing linkage systems for drug conjugates. WO2015095953A1.
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