ChemicalBook--->CAS DataBase List--->18358-63-9

18358-63-9

18358-63-9 Structure

18358-63-9 Structure
IdentificationMore
[Name]

METHYL 4-METHYLAMINOBENZOATE
[CAS]

18358-63-9
[Synonyms]

4-(METHYLAMINO)-BENZOIC ACID METHYL ESTER
METHYL 4-METHYLAMINOBENZOATE
METHYL 4-(N-METHYLAMINO)BENZOATE
Benzoic acid, 4-(methylamino)-, methyl ester
p-Aminobenzoic acid di-methyl derivative
METHYL 4-(AMINOMETHYL)-2-CHLOROBENZOATE
[Molecular Formula]

C9H11NO2
[MDL Number]

MFCD00017198
[Molecular Weight]

165.19
[MOL File]

18358-63-9.mol
Chemical PropertiesBack Directory
[Melting point ]

94-96°C
[Boiling point ]

277.5±23.0 °C(Predicted)
[density ]

1.125±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

2.26±0.12(Predicted)
[color ]

White to Light Brown
[Water Solubility ]

It is slightly soluble in water. (1.2 g/L) (25°C insoluble in hexane.
[BRN ]

2803327
[InChI]

InChI=1S/C9H11NO2/c1-10-8-5-3-7(4-6-8)9(11)12-2/h3-6,10H,1-2H3
[InChIKey]

LLAMGYUWYUMHCH-UHFFFAOYSA-N
[SMILES]

C(OC)(=O)C1=CC=C(NC)C=C1
[CAS DataBase Reference]

18358-63-9(CAS DataBase Reference)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Methanol-->Dichloromethane-->N,N-Dimethylformamide-->Thionyl chloride-->Triethylamine-->Ammonium chloride-->Acetonitrile-->Sodium hydride-->Iodomethane-->p-Toluenesulfonic acid-->Di-tert-butyl dicarbonate-->Trifluoroacetic acid-->4-Dimethylaminopyridine-->4-Aminobenzoic acid
[Preparation Products]

methyl sulfamate-->4-(Methylamino)benzoic acid-->Methyl 4-(tert-butoxycarbonyl(methyl)amino)benzoate-->DAMPA Methyl Ester
Safety DataBack Directory
[HazardClass ]

IRRITANT
[HS Code ]

2916310090
Hazard InformationBack Directory
[Uses]

Methyl 4-(Methylamino)benzoate is used as a reagent in the synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5. Also used in the preparation of hyaluronic acid-methotrexate conjugates as antiarthritic and antiinflammatory agents.This compound is suitable for lactate dehydrogenase (LDH) related research.
Spectrum DetailBack Directory
[Spectrum Detail]

METHYL 4-METHYLAMINOBENZOATE(18358-63-9)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

Methyl 4-(methylamino)benzoate, 98%(18358-63-9)
[Sigma Aldrich]

18358-63-9(sigmaaldrich)
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