| Hazard Information | Back Directory | [Description]
SM-32504 is a potent ACAT inhibitor. | [Uses]
SM-32504 is an effective ACAT inhibitor that can significantly reduce serum cholesterol levels in mouse models fed with high-fat and high-cholesterol diets. SM-32504 can be used for research on hypercholesterolemia and atherosclerosis[1]. | [References]
[1] Ohnuma S, et al. Synthesis and structure–activity relationship studies on a novel series of naphthylidinoylureas as inhibitors of acyl-CoA: cholesterol O-acyltransferase (ACAT)[J]. Bioorganic & medicinal chemistry letters, 2004, 14(5): 1309-1311. DOI:10.1016/j.bmcl.2003.12.045 |
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