| Identification | Back Directory | [Name]
SU 5214 | [CAS]
186611-04-1 | [Synonyms]
SU4949
SU 5214
SU 5214;SU-5214;SU5214
2H-Indol-2-one, 1,3-dihydro-3-[(2-methoxyphenyl)methylene]- | [Molecular Formula]
C16H13NO2 | [MDL Number]
MFCD01595259 | [MOL File]
186611-04-1.mol | [Molecular Weight]
251.28 |
| Chemical Properties | Back Directory | [Boiling point ]
469.4±45.0 °C(Predicted) | [density ]
1.238±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMF: 33 mg/ml; DMSO: 33 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml | [form ]
A crystalline solid | [pka]
12.81±0.20(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
SU5214 is a potent VEGFR2 inhibitor extracted from patent US5834504A, SU5214, has IC50s of 14.8 μM (FLK-1) and 36.7 μM (EGFR), respectively[1]. | [IC 50]
Flk-1: 14.8 μM (IC50) | [References]
[1] Tang et al. 3-(2'-halobenzylidenyl)-2-indolinone compounds for the treatment of disease. US5834504A. |
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