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186611-11-0

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186611-11-0 Structure

186611-11-0 Structure
IdentificationBack Directory
[Name]

su5204
[CAS]

186611-11-0
[Synonyms]

2H-Indol-2-one, 3-[(2-ethoxyphenyl)methylene]-1,3-dihydro-
[Molecular Formula]

C17H15NO2
[MDL Number]

MFCD04651331
[MOL File]

186611-11-0.mol
[Molecular Weight]

265.31
Chemical PropertiesBack Directory
[Boiling point ]

476.9±45.0 °C(Predicted)
[density ]

1.209±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

DMSO: 100 mg/mL (376.92 mM)
[form ]

Solid
[pka]

12.82±0.20(Predicted)
[color ]

Light yellow to yellow
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

SU5204, a tyrosine kinase inhibitor, has IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively[1].
[IC 50]

VEGFR2: 4 μM (IC50); HER2: 51.5 μM (IC50)
[References]

[1] Peng Cho Tang, et al. 3-heteroaryl-2-indolinone compounds for the treatment of disease. US5792783A.
Spectrum DetailBack Directory
[Spectrum Detail]

su5204(186611-11-0)1HNMR
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