ChemicalBook--->CAS DataBase List--->1875067-34-7

1875067-34-7

1875067-34-7 Structure

1875067-34-7 Structure
IdentificationBack Directory
[Name]

BMS-770767
[CAS]

1875067-34-7
[Synonyms]

BMS-770767
BMS-770767 >=98% (HPLC)
Bicyclo[2.2.1]heptan-1-ol, 4-[8-(2-chlorophenoxy)-1,2,4-triazolo[4,3-a]pyridin-3-yl]-
[Molecular Formula]

C19H18ClN3O2
[MDL Number]

MFCD30480905
[MOL File]

1875067-34-7.mol
[Molecular Weight]

355.82
Chemical PropertiesBack Directory
[density ]

1.48±0.1 g/cm3(Predicted)
[storage temp. ]

room temp
[form ]

powder
[pka]

14.69±0.40(Predicted)
[color ]

white to beige
Hazard InformationBack Directory
[Uses]

BMS-770767 is an 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor in type 2 diabetes. 11β-HSD1 is an important enzyme that is widely expressed in liver, adipose tissue and other tissues and plays an important role in metabolic diseases such as diabetes and obesity[1].
[References]

[1] Brad D Maxwell, et al. The synthesis and analysis of [phenyl-14?C(U)]BMS-770767 and [13?C6?]BMS-770767 for use in discovery biotransformation, human ADME and bioanalytical studies. J Labelled Comp Radiopharm. 2016 Dec;59(14):657-664. DOI:10.1002/jlcr.3428
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