| Identification | Back Directory | [Name]
Kumbicin C | [CAS]
1878151-58-6 | [Synonyms]
Kumbicin C
5,8-di-1H-indol-3-yl-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-ol | [Molecular Formula]
C28H24N2O3 | [MOL File]
1878151-58-6.mol | [Molecular Weight]
436.5 |
| Chemical Properties | Back Directory | [Boiling point ]
710.8±60.0 °C(Predicted) | [density ]
1.295±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
A solid | [pka]
10.44±0.40(Predicted) |
| Hazard Information | Back Directory | [Description]
Kumbicin C is a bis-indolyl benzenoid fungal metabolite produced by A. kumbius FRR6049. It inhibits the growth of NS-1 mouse myeloma cells (IC50 = 0.74 μg/ml). Kumbicin C also inhibits the growth of the Gram-positive bacteria B. subtilis (MIC = 1.6 μg/ml). | [Uses]
Kumbicin C is a bis-indolyl benzenoid compound from an Australian soil fungus, Aspergillus kumbius. Kumbicin C inhibits the growth of mouse myeloma cells and the Gram-positive bacterium Bacillus subtilis[1]. | [storage]
Store at -20°C | [References]
[1] Heather J. Lacey, et al. Kumbicins A–D: Bis-Indolyl Benzenoids and Benzoquinones from an Australian Soil Fungus, Aspergillus kumbius. |
|
|