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188057-20-7

188057-20-7 Structure

188057-20-7 Structure
IdentificationBack Directory
[Name]

4-IODO-PYRIDIN-3-OL
[CAS]

188057-20-7
[Synonyms]

AKOS A0602-0922
2-Iodo-3-pyridinol
4-IODO-PYRIDIN-3-OL
3-Pyridinol, 4-iodo-
2-Iodo-3-hydroxypyridine
3-Hydroxy-4-iodopyridine
4-IODO-3-HYDROXYPYRIDINE
4-IODO-PYRIDIN-3-OL ISO 9001:2015 REACH
[Molecular Formula]

C5H4INO
[MDL Number]

MFCD09030242
[MOL File]

188057-20-7.mol
[Molecular Weight]

220.996
Chemical PropertiesBack Directory
[Melting point ]

196-200℃
[Boiling point ]

296.6±20.0 °C(Predicted)
[density ]

2.142±0.06 g/cm3(Predicted)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2–8 °C
[pka]

6.87±0.10(Predicted)
[Appearance]

Off-white to light yellow Solid
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictograms
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
[Hazard Codes ]

Xn
[Risk Statements ]

22-37/38-41
[Safety Statements ]

26-39
Hazard InformationBack Directory
[Description]

4-Iodo-3-hydroxypyridine is an organic intermediate, commonly used in the synthesis of various pharmaceutical and chemical products. It is reported in the literature that 4-iodo-3-hydroxypyridine can be prepared from 2-chloro-4-iodopyridine in one step or from 3-hydroxypyridine in three steps.

[Application]

4-Iodo-3-hydroxypyridine is an organic intermediate and pharmaceutical intermediate, which is commonly used in the synthesis of various pharmaceutical and chemical products and in laboratory research and development processes.
[Synthesis]

4-Iodo-3-hydroxypyridine can be prepared by reacting 3-hydroxypyridine, potassium tert-butoxide, and methoxymethyl chloride in a nitrogen atmosphere.
[References]

[1] Patent: US2010/93720, 2010, A1. Location in patent: Page/Page column 57
[2] Journal of Organic Chemistry, 2005, vol. 70, # 2, p. 489 - 498
Spectrum DetailBack Directory
[Spectrum Detail]

4-IODO-PYRIDIN-3-OL(188057-20-7)1HNMR
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