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1883518-31-7

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1883518-31-7 Structure

1883518-31-7 Structure
IdentificationBack Directory
[Name]

GNE-0723
[CAS]

1883518-31-7
[Synonyms]

GNE-0723
[Molecular Formula]

C16H8ClF6N5OS
[MDL Number]

MFCD30829912
[MOL File]

1883518-31-7.mol
[Molecular Weight]

467.78
Chemical PropertiesBack Directory
[Boiling point ]

505.2±60.0 °C(Predicted)
[density ]

1.84±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

-0.82±0.70(Predicted)
[color ]

White to yellow
Hazard InformationBack Directory
[Uses]

EC50: 21 nM (GluN2A), 7.4 μM (GluN2C), 6.2 μM (GluN2D)

[Biological Activity]

GNE-0723 is a positive regulator of blood-brain barrier permeable NMDARs with EC50 values of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.
[in vitro]

GNE-0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC 50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.

[IC 50]

NMDA Receptor
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

GNE-0723(1883518-31-7)1HNMR
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