ChemicalBook--->CAS DataBase List--->188425-80-1

188425-80-1

188425-80-1 Structure

188425-80-1 Structure
IdentificationBack Directory
[Name]

st-Ht31
[CAS]

188425-80-1
[Synonyms]

st-Ht31
[Molecular Formula]

C129H217N29O39
[MOL File]

188425-80-1.mol
[Molecular Weight]

2798.32
Chemical PropertiesBack Directory
[density ]

1.37±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Uses]

st-Ht31 is a membrane-permeable peptide inhibitor of protein kinase A (PKA) anchoring. st-Ht31 induces robust cholesterol/phospholipid efflux. st-Ht31 completely reverses foam cell formation and restores the metabolic health of macrophage[1][2].
[storage]

Store at -20°C
[References]

[1] Ma L, et al. Ht31, a protein kinase A anchoring inhibitor, induces robust cholesterol efflux and reverses macrophage foam cell formation through ATP-binding cassette transporter A1. J Biol Chem. 2011 Feb 4;286(5):3370-8. DOI:10.1074/jbc.M110.173666
[2] Rahamim Ben-Navi L, et al. A-Kinase Anchoring Protein 4 (AKAP4) is an ERK1/2 substrate and a switch molecule between cAMP/PKA and PKC/ERK1/2 in human spermatozoa. Sci Rep. 2016 Nov 30;6:37922. DOI:10.1038/srep37922
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