| Identification | Back Directory | [Name]
Carbonic acid, bicyclo[2.2.1]hept-5-en-2-yl (2,5-dioxo-1-pyrrolidinyl) ester | [CAS]
1888335-48-5 | [Synonyms]
Norbornene-NHS
Carbonic acid, bicyclo[2.2.1]hept-5-en-2-yl (2,5-dioxo-1-pyrrolidinyl) ester | [Molecular Formula]
C12H13NO5 | [MOL File]
1888335-48-5.mol | [Molecular Weight]
251.24 |
| Chemical Properties | Back Directory | [Boiling point ]
355.9±45.0 °C(Predicted) | [density ]
1.42±0.1 g/cm3(Predicted) | [form ]
Liquid
(Density: 1.42±0.1 g/cm3) | [color ]
Light yellow to yellow | [InChI]
1S/C12H13NO5/c14-10-3-4-11(15)13(10)18-12(16)17-9-6-7-1-2-8(9)5-7/h1-2,7-9H,3-6H2 | [InChIKey]
UFPOHRPAWSDIKK-UHFFFAOYSA-N | [SMILES]
O=C(ON1C(=O)CCC1=O)OC2CC3C=CC2C3 |
| Hazard Information | Back Directory | [Uses]
Norbornene-NHS is a click chemistry reagent. Norbornene-NHS is a dienophile for conjugation via copper-free Click reaction with tetrazines[1]. | [References]
[1] Heil CS, et al. Site-Specific Labelling of Multidomain Proteins by Amber Codon Suppression. Sci Rep. 2018 Oct 5;8(1):14864. DOI:10.1038/s41598-018-33115-5 |
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