| Identification | Back Directory | [Name]
2',6'-DIHYDROXY-4'-METHOXYCHALCONE | [CAS]
18956-15-5 | [Synonyms]
Pistrobin chalcone
plnostrobin chalcone
Pinostrobin chalcone
2-Propen-1-one,1-(2,6-dihy
2',6'-DIHYDROXY-4'-METHOXYCHALCONE
DIHYDROXY-4'-METHOXYCHALCONE, 2',6'-
(E)-2',6'-Dihydroxy-4'-methoxychalcone
(E)-1-(2,6-Dihydroxy-4-methoxy-phenyl)-3-phenyl-
(E)-1-(2,6-DIHYDROXY-4-METHOXY-PHENYL)-3-PHENYL-PROPENONE
1-(2,6-Dihydroxy-4-Methoxyphenyl)-3-phenylprop-2-en-1-one
2-Propen-1-one, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenyl-, (2E)- | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C16H14O4 | [MDL Number]
MFCD00017363 | [MOL File]
18956-15-5.mol | [Molecular Weight]
270.28 |
| Chemical Properties | Back Directory | [Melting point ]
145°C | [Boiling point ]
521.1±50.0 °C(Predicted) | [density ]
1.282±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: Soluble: =10 mg/ml
Ethanol: Soluble: =10 mg/ml | [form ]
Solid | [pka]
6.70±0.40(Predicted) | [color ]
Light yellow to orange | [InChI]
1S/C16H14O4/c1-20-12-9-14(18)16(15(19)10-12)13(17)8-7-11-5-3-2-4-6-11/h2-10,18-19H,1H3/b8-7+ | [InChIKey]
CUGDOWNTXKLQMD-BQYQJAHWSA-N | [SMILES]
O(C)c1cc(c(c(c1)O)C(=O)\C=C\c2ccccc2)O |
| Hazard Information | Back Directory | [Uses]
Pinostrobin Chalcone is an estrogenic compound from the plant leaves of Carya cathayensis Sarg. | [Definition]
ChEBI: Pinostrobin chalcone is a member of chalcones. | [References]
[1] BARAA M. I. S. JADALLA. In Vitro Alpha-Glucosidase and Alpha-Amylase Inhibitory Activities and Antioxidant Capacity of Helichrysum cymosum and Helichrysum pandurifolium Schrank Constituents[J]. Separations, 2022. DOI: 10.3390/separations9080190
[2] E C TORRES-SANTOS. Selective effect of 2’,6’-dihydroxy-4’-methoxychalcone isolated from Piper aduncum on Leishmania amazonensis.[J]. Antimicrobial Agents and Chemotherapy, 1999, 43 5: 1234-1241. DOI: 10.1128/aac.43.5.1234
[3] SRI NURESTRI ABDUL MALEK. Phytochemical and cytotoxic investigations of Alpinia mutica rhizomes.[J]. Molecules, 2011, 16 1: 583-589. DOI: 10.3390/molecules16010583
[4] NEERAJ K. PATEL Kamlesh K B. Pinostrobin and Cajanus lactone isolated from Cajanus cajan (L.) leaves inhibits TNF-α and IL-1β production: In vitro and in vivo experimentation[J]. Phytomedicine, 2014, 21 7: Pages 946-953. DOI: 10.1016/j.phymed.2014.02.011 |
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