| Identification | More | [Name]
3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE | [CAS]
855-96-9 | [Synonyms]
3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE
5,3'-DIHYDROXY-6,7,4'-TRIMETHOXYFLAVONE
EUPATORIN
EUPATORIN 97%
5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one
6-Hydroxyluteolin 4',6,7-trimethyl ether | [EINECS(EC#)]
663-133-9 | [Molecular Formula]
C18H16O7 | [MDL Number]
MFCD00016929 | [Molecular Weight]
344.32 | [MOL File]
855-96-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
194-196°C | [Boiling point ]
587.0±50.0 °C(Predicted) | [density ]
1.387±0.06 g/cm3(Predicted) | [storage temp. ]
room temp | [solubility ]
DMSO: >10mg/mL | [form ]
powder | [pka]
6.31±0.40(Predicted) | [color ]
white to beige | [Water Solubility ]
Insoluble in water. Soluble in chloroform and methanol. | [Merck ]
14,3901 | [BRN ]
1355109 | [InChI]
1S/C18H16O7/c1-22-12-5-4-9(6-10(12)19)13-7-11(20)16-14(25-13)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3 | [InChIKey]
KLAOKWJLUQKWIF-UHFFFAOYSA-N | [SMILES]
COc1ccc(cc1O)C2=CC(=O)c3c(O)c(OC)c(OC)cc3O2 | [LogP]
2.960 (est) | [CAS DataBase Reference]
855-96-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
1 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Solid | [Uses]
3',5-Dihydroxy-4',6,7-trimethoxyflavone is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals. | [Uses]
Eupatorin is a flavanoid with antiproliferative activity in cells expressing the CYP1 family. Eupatorin also displays antioxidant and anti-inflammatory activity. | [Definition]
ChEBI: Eupatorin is a trimethoxyflavone that is 6-hydroxyluteolin in which the phenolic hydogens at positions 4', 6 and 7 have been replaced by methyl groups. It has a role as a Brassica napus metabolite, an apoptosis inducer, a vasodilator agent, a calcium channel blocker, an anti-inflammatory agent, a P450 inhibitor and an antineoplastic agent. It is a dihydroxyflavone, a trimethoxyflavone and a polyphenol. It is functionally related to a 6-hydroxyluteolin. | [Biological Activity]
Eupatorin acts as an antiproliferative in cells expressing the CYP1A- family. It induces G2/M block follow by apoptosis in cells expressing the CYP1A- family. It also functions as an anti-inflammatory. |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|