| Identification | Back Directory | [Name]
8H-1,4-Dioxino[2,3-e]indol-8-one, 2,3,7,9-tetrahydro-2-[[(phenylmethyl)amino]methyl]-, (2S)- | [CAS]
189681-70-7 | [Synonyms]
8H-1,4-Dioxino[2,3-e]indol-8-one, 2,3,7,9-tetrahydro-2-[[(phenylmethyl)amino]methyl]-, (2S)- | [Molecular Formula]
C18 H18 N2 O3 | [MOL File]
189681-70-7.mol | [Molecular Weight]
310.35 |
| Hazard Information | Back Directory | [Uses]
Aplindore (DAB-452) is a potent agonist of the dopamine D2 receptor, with the pKi of 9.1. Aplindore plays an important role in Parkinson's disease research[1]. | [IC 50]
D2 Receptor: 9.1 (pKi) | [References]
[1] Julia N Heinrich, et al. Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist. Eur J Pharmacol. 2006 Dec 15;552(1-3):36-45. DOI:10.1016/j.ejphar.2006.08.063 |
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