| Identification | Back Directory | [Name]
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- | [CAS]
1914989-80-2 | [Synonyms]
Aβ42-IN-2
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- | [Molecular Formula]
C24H26N6O2 | [MDL Number]
MFCD32857167 | [MOL File]
1914989-80-2.mol | [Molecular Weight]
430.5 |
| Chemical Properties | Back Directory | [Boiling point ]
651.4±55.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, stored under nitrogen | [solubility ]
DMSO : 20 mg/mL (46.46 mM; Need ultrasonic) | [form ]
Solid | [pka]
4.22±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC50 of 6.5 nM for αβ42. Aβ42-IN-2 can be used for the research of Alzheimer’s disease[1]. | [References]
[1]. Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1. |
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| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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