| Chemical Properties | Back Directory | [Boiling point ]
475.0±45.0 °C(Predicted) | [density ]
1.283±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 41.67 mg/mL (140.14 mM) | [pka]
13.05±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
CP-409092 is a partial agonist of GABAA receptor, with anti-anxiety activity[1]. | [in vivo]
The pharmacokinetics of CP-409,092 following single intravenous and oral doses of 4 and 15 mg/kg, respectively, are characterized by high clearance of 169+ or -18 mL/min/kg, a volume of distribution of 8.99+ or -1.46 L/kg, and an oral bioavailability of 2.9%+ or -3%. Following oral administration of 100 mg/kg [14C]CP-409,092, the total recovery is 89.1%+ or -3.2% for male rats and 89.3%+ or -0.58% for female rats[1]. | [storage]
Store at -20°C | [References]
[1] Kamel A, et al. Metabolism, pharmacokinetics and excretion of the GABA(A) receptor partial agonist [(14)C]CP-409,092 in rats. Xenobiotica. 2010 Jun;40(6):400-14. DOI:10.3109/00498251003710269 |
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cjbscvictory
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13348960310 13348960310; |
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https://www.weikeqi-biotech.com/ |
| Company Name: |
MedChemExpress
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021-58955995 |
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www.medchemexpress.com |
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