| Identification | Back Directory | [Name]
SAR405 R enantiomer | [CAS]
1946010-79-2 | [Synonyms]
SAR405 R enantiomer
4H-Pyrimido[1,2-a]pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-, (8R)- | [Molecular Formula]
C19H21ClF3N5O2 | [MDL Number]
MFCD29037449 | [MOL File]
1946010-79-2.mol | [Molecular Weight]
443.85 |
| Chemical Properties | Back Directory | [Boiling point ]
526.5±60.0 °C(Predicted) | [density ]
1.51±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
3.29±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is a PIK3C3/Vps34 inhibitor. | [References]
[1] Pasquier B. SAR405, a PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells. Autophagy. 2015 Apr 3;11(4):725-6. DOI:10.1080/15548627.2015.1033601 |
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Henan Alfachem Co.,Ltd.
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InvivoChem
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https://www.invivochem.cn/ |
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