| Identification | More | [Name]
4-Methoxyphenylhydrazine hydrochloride | [CAS]
19501-58-7 | [Synonyms]
1-(4-METHOXYPHENYL)HYDRAZINE HYDROCHLORIDE
4-ANISYLHYDRAZINE HYDROCHLORIDE
4-HYDRAZINOANISOLE HYDROCHLORIDE
4-METHOXYPHENYLHYDRAZINE HCL
4-METHOXYPHENYLHYDRAZINE HYDROCHLORIDE
4-METHOXYPHENYLHYDRAZINIUM HYDROCHLORIDE
AURORA KA-1052
PARA METHOXY PHENYL HYDRAZINE HYDROCHLORIDE
P-METHOXY-PHENYLHYDRAZINE-HYDROCHLORIDE
P-METHOXYPHENYLHYDRAZINIUM CHLORIDE
4-Methoxyphenyhydrozine HCL
4-Methoxyphenylhydrazine Hcl 98 %
Hydrazine, (4-methoxyphenyl)-, monohydrochloride
4-Methoxyphenylhydrazine hydrochloride 98%
4-Methoxyphenylhydrazinehydrochloride98%
4-Methoxyphenylhydrazinehydrochloridel
p-Methoxy phenyl hydrazine hydrocloride | [EINECS(EC#)]
243-115-3 | [Molecular Formula]
C7H11ClN2O | [MDL Number]
MFCD00012945 | [Molecular Weight]
174.63 | [MOL File]
19501-58-7.mol |
| Chemical Properties | Back Directory | [Appearance]
slightly pink to greyish-purple powder | [Melting point ]
160-162 °C (dec.)(lit.)
| [storage temp. ]
Keep Cold | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Powder, Crystals and/or Chunks | [color ]
Slightly pink to gray to purple | [Water Solubility ]
soluble | [Detection Methods]
NMR | [BRN ]
3566583 | [Stability:]
Light Sensitive | [InChI]
InChI=1S/C7H10N2O.ClH/c1-10-7-4-2-6(9-8)3-5-7;/h2-5,9H,8H2,1H3;1H | [InChIKey]
FQHCPFMTXFJZJS-UHFFFAOYSA-N | [SMILES]
C1(NN)=CC=C(OC)C=C1.Cl | [CAS DataBase Reference]
19501-58-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302+H312+H332-H317 | [Precautionary statements ]
P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
2811 | [WGK Germany ]
3
| [Hazard Note ]
Irritant/Harmful | [HazardClass ]
IRRITANT, KEEP COLD | [PackingGroup ]
III | [HS Code ]
29280090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Skin Sens. 1 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
p-Anisidine-->Hydrochloric acid-->Sodium nitrite-->Stannous chloride | [Preparation Products]
1-(4-Methoxyphenyl)-5-methyl-1H-pyrazole-4-carbaldehyde-->2,3,4,9-tetrahydro-6-methoxy-1H-pyrido[3,4-b]indol-1-one-->5-Methoxy-2-methylindole-->2,3,3-Trimethyl-5-methoxy-3H-indole-->6-Methoxy-1,2,3,4-tetrahydro-beta-carboline-->Tepoxalin-->Acemetacin-->2H-Imidazole-2-thione, 1,3-dihydro-1-[(4-methoxyphenyl)amino]-4-methyl-5-phenyl--->Ethyl 1-(4-methoxyphenyl)-5-(trifluoromethyl)pyrazole-4-carboxylate-->(5-Methoxy-2-methyl-1H-indol-3-yl)-acetic acid ethyl ester |
| Hazard Information | Back Directory | [Description]
4-Methoxyphenylhydrazine hydrochloride is a kind of midbody that is mainly used for producing phenylhydrazine, and can also be used to make other Chemicals. The reparation technology of 4-Methoxyphenylhydrazine hydrochloride comprises aniline diazonium and benzene diazonium chloride diazo benzene chloride two-step process.
| [Chemical Properties]
slightly pink to greyish-purple powder | [Uses]
4-Methoxyphenylhydrazine hydrochloride was used in the preparation of 5-cyano-3-(5-methoxy-2-methylindol-3-yl)-1,2,4-thiadiazole. | [Synthesis]
4-Methoxyphenylhydrazine hydrochloride Preparation Process: Take hydrochloric acid and sodium nitrite and add them sequentially to aniline, where the molar ratio of aniline to hydrochloric acid to sodium nitrite is 1:2.3 to 3.2:1 to 1.1, and sodium nitrite is added at 0 to 5°C. The reaction temperature is 0 to 22°C, and the reaction time is 30 to 90 minutes. Then add ammonium sulfite and hydrochloric acid according to a molar ratio to aniline of 1:2 to 3.5:2.5 to 3.0. After reduction, hydrolysis, and acidification, the product can be obtained by filtration or centrifugation. | [References]
[1] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 13, p. 3322 - 3336
[2] Journal of Heterocyclic Chemistry, 1995, vol. 32, # 1, p. 1 - 11
[3] Russian Chemical Bulletin, 2005, vol. 54, # 10, p. 2417 - 2424
[4] European Journal of Medicinal Chemistry, 2010, vol. 45, # 10, p. 4692 - 4696
[5] Journal of Organic Chemistry, 2011, vol. 76, # 13, p. 5295 - 5308 |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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