Identification | Back Directory | [Name]
AP1867 | [CAS]
195514-23-9 | [Synonyms]
AP1867 2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, (1R)-1-[3-(carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)- | [Molecular Formula]
C38H47NO11 | [MOL File]
195514-23-9.mol | [Molecular Weight]
693.78 |
Chemical Properties | Back Directory | [Boiling point ]
814.2±65.0 °C(Predicted) | [density ]
1.214±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C, protect from light | [solubility ]
DMSO : ≥ 125 mg/mL (180.17 mM);Water : < 0.1 mg/mL (insoluble) | [form ]
Solid | [pka]
3.14±0.10(Predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Uses]
AP1867 is a synthetic FKBP12F36V-directed ligand[1]. | [storage]
-20°C, protect from light | [References]
[1] Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441. DOI:10.1038/s41589-018-0021-8 [2] Koide K, et al. A synthetic library of cell-permeable molecules. J Am Chem Soc. 2001 Jan 24;123(3):398-408. DOI:10.1021/ja0023377 |
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Company Name: |
Wuhan Topule
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+86-02787215551 +86-19945035818 |
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http://www.topule.com/ |
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