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195514-23-9

195514-23-9 Structure

195514-23-9 Structure
IdentificationBack Directory
[Name]

AP1867
[CAS]

195514-23-9
[Synonyms]

AP1867
2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, (1R)-1-[3-(carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-
[Molecular Formula]

C38H47NO11
[MOL File]

195514-23-9.mol
[Molecular Weight]

693.78
Chemical PropertiesBack Directory
[Boiling point ]

814.2±65.0 °C(Predicted)
[density ]

1.214±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C, protect from light
[solubility ]

DMSO : ≥ 125 mg/mL (180.17 mM);Water : < 0.1 mg/mL (insoluble)
[form ]

Solid
[pka]

3.14±0.10(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

AP1867 is a synthetic FKBP12F36V-directed ligand[1].
[storage]

-20°C, protect from light
[References]

[1] Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441. DOI:10.1038/s41589-018-0021-8
[2] Koide K, et al. A synthetic library of cell-permeable molecules. J Am Chem Soc. 2001 Jan 24;123(3):398-408. DOI:10.1021/ja0023377
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