| Identification | Back Directory | [Name]
4-Pentynoyl-Val-Ala-PAB-PNP | [CAS]
1956294-76-0 | [Synonyms]
4-Pentynoyl-Val-Ala-PAB-PNP
L-Alaninamide, N-(1-oxo-4-pentynyl)-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- | [Molecular Formula]
C27H30N4O8 | [MOL File]
1956294-76-0.mol | [Molecular Weight]
538.55 |
| Hazard Information | Back Directory | [Uses]
4-Pentynoyl-Val-Ala-PAB-PNP is a cleavable ADC linker, that has been used to synthesis cryptophycin conjugates[1]. 4-Pentynoyl-Val-Ala-PAB-PNP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
Cleavable Linker | [References]
[1] Cedric DESSIN, et al. Cryptophycin compounds and conjugates thereof. WO2022175222 |
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