| Identification | More | [Name]
Uridine-5'-triphosphoric acid trisodium salt | [CAS]
19817-92-6 | [Synonyms]
URIDINE 5'-TRIPHOSPHATE TETRASODIUM
URIDINE-5'-TRIPHOSPHATE TETRASODIUM SALT
Uridine 5'-triphosphatetrisodium salthydrate
Uridine-5'-triphosphoric acid trisodium salt
uridine 5'-(disodium dihydrogen triphosphate)
URIDINE 5'-TRIPHOSPHATE TRISODIUM*100 MM SOLUTION M
URIDINE 5'-TRIPHOSPHATE TYPE IV*TRISODIU M
URIDINE 5'-TRIPHOSPHATE SODIUM FROM*YEAS T TYPE III
URIDINE-5'-TRIPHOSPATE (UTP) TRISODIUM SALT, ULTRA PURE GRADE 98+% (DRY BASIS)
URIDINE-5'-TRIPHOSPATE (UTP) TRISODIUM SALT, CULTURE REAGENT 98%
URIDINE-5'-TRIPHOSPATE (UTP) TRISODIUM SALT, 97%
URIDINE-5'-TRIPHOSPATE (UTP), 100MM SOLUTION
Uridine 5-(tetrahydrogen triphosphate), trisodium salt
utp na3
URIDINE-5''-TRIPHOSPHATE TRISODIUM SALT DIHYDRATE (UTP)
URIDINE-5'-TRIPHOSPHATE TRISODIUM SALT DIHYDRATE extrapure
Uridine 5μ-triphosphate hydrate trisodium salt
UTP, 100mM Solution | [EINECS(EC#)]
243-347-5 | [Molecular Formula]
C9H12N2Na3O15P3 | [MDL Number]
MFCD06200764 | [Molecular Weight]
550.09 | [MOL File]
19817-92-6.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
140 °C | [Fp ]
113 °C | [storage temp. ]
−20°C
| [solubility ]
H2O: soluble25 mg of UTP in 0.5 ml of solvent, clear, colorless | [form ]
Powder | [color ]
White | [biological source]
yeast | [Water Solubility ]
75 g/100 mL (20 ºC) | [BRN ]
3585234 | [InChIKey]
IKVGSWYKOMJBSB-RFFBCSJBNA-N | [SMILES]
O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,19,r| | [CAS DataBase Reference]
19817-92-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R68/20/21/22:Harmful: possible risk of irreversible effects through inhalation, in contact with skin and if swallowed .
R68:Possible risk of irreversible effects.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
1
| [RTECS ]
YU8083000 | [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Description]
Uridine-5'-triphosphoric acid trisodium salt (19817-92-6), also known as UTP, is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors.
| [Chemical Properties]
White crystalline powder | [Uses]
Uridine-5'-triphosphoric acid trisodium salt (19817-92-6) is a polyphosphate analogue of the nucleoside uridine used in the preparation of potent and selective agonists at the G-protein-coupled P2Y receptors.
| [Uses]
??? | [Uses]
P2Y receptor agonist. | [Uses]
psychostimulant | [Application]
Uridine-5'-triphosphoric acid trisodium salt (19817-92-6) solution can be used to increase intracellular Ca2+ levels in rat primary tracheal epithelial cells. It is also used as a nucleotide substrate to analyze the activity of MutT homolog 1 (MTH1).
| [Biochem/physiol Actions]
Uridine-5′-Triphosphate?(UTP,19817-92-6) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space. Uridine-5′-Triphosphate?(UTP) is involved in various pathophysiological responses in the nervous system.?UTP also plays a major role in the regeneration process.
| [in vitro]
Uridine triphosphate (UTP) (0, 10, 100, 250, 500, and 1000 μM; 2, 4, 6, 8, 10, and 12 h) trisodium salt enhances RT4-D6P2T cells migration and wound repair. Uridine triphosphate trisodium salt induces Schwannoma cell migration through the activation of P2Y2 receptors and the increase of extracellular MMP-2 activation and expression. Uridine triphosphate (UTP) trisodium salt (Uridine-5'-triphosphoric acid trisodium salt) evokes MAPK phosphorylation in a biphasic pattern MAPK phosphorylation, with an early transient phosphorylation 5 min after treatment and a late and sustained phosphorylation that appeared at 6 h and lasted up to 24 h. | [Structure and conformation]
Uridine-5'-triphosphoric acid trisodium salt is composed of uridine (a nucleoside) combined with three phosphate groups and exists in the form of trisodium salt. This structure makes it well soluble in aqueous solution, and the negatively charged phosphate groups can participate in a variety of important energy transfer processes in biochemical reactions. |
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