| Identification | Back Directory | [Name]
L-Phenylalanine, L-tyrosylglycyl-L-leucyl- | [CAS]
198284-23-0 | [Synonyms]
L-Phenylalanine, L-tyrosylglycyl-L-leucyl- | [Molecular Formula]
C26H34N4O6 | [MOL File]
198284-23-0.mol | [Molecular Weight]
498.571 |
| Hazard Information | Back Directory | [Uses]
Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is a blood pressure lowering peptide containing 4 amino acids. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is an angiotensin-converting Enzyme (ACE) inhibitor. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine can be used in research of high blood pressure[1]. | [in vivo]
Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine (1-1000 μg/kg; s.c.) inhibits blood pressure in normotensive and spontaneously hypertensive rats[1]. | Animal Model: | Adult male SHR and WKY rats[1] | | Dosage: | 1, 10, 100, and 1000 μg/kg | | Administration: | Subcutaneous injection | | Result: | Inhibited blood pressure in a dose-dependent manner. |
| [References]
[1] Nurminen MN, et, al. α-Lactorphin lowers blood pressure measured by radiotelemetry in normotensive and spontaneously hypertensive rats. Life Sciences. 2000 Mar 10;66(16):1535-43. |
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