| Identification | More | [Name]
5-Nitro-3-pyrazolecarboxylic acid | [CAS]
198348-89-9 | [Synonyms]
5-NITRO-3-PYRAZOLECARBOXYLIC ACID
AKOS B006514
TIMTEC-BB SBB004010
5-NITRO-3-PYRAZOLECARBOXYLIC ACID 98%
1H-Pyrazole-3-carboxylicacid,5-nitro-(9CI) | [EINECS(EC#)]
607-884-2 | [Molecular Formula]
C4H3N3O4 | [MDL Number]
MFCD00192356 | [Molecular Weight]
157.08 | [MOL File]
198348-89-9.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white to light yellow crystalline powder | [Melting point ]
188-190 °C(lit.) | [Boiling point ]
509.6±35.0 °C(Predicted) | [density ]
1.840±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
solid | [pka]
3.22±0.10(Predicted) | [color ]
Slightly yellow | [InChI]
InChI=1S/C4H3N3O4/c8-4(9)2-1-3(6-5-2)7(10)11/h1H,(H,5,6)(H,8,9) | [InChIKey]
HKYHBMLIEAMWRO-UHFFFAOYSA-N | [SMILES]
N1C([N+]([O-])=O)=CC(C(O)=O)=N1 | [CAS DataBase Reference]
198348-89-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [HazardClass ]
IRRITANT | [HS Code ]
2933119000 |
| Hazard Information | Back Directory | [Chemical Properties]
off-white to light yellow crystalline powder | [Uses]
5-Nitro-1H-pyrazole-3-carboxylic acid was investigated for potential therapeutic properties on ocular blood flow and retinal function recovery after reperfusion injury and ischemic insult. | [Synthesis]
3-Methyl-5-nitrothiazole (0.18 mol) was dissolved in concentrated H2SO4 (300 mL) and Na2Cr2O7-2H2O (53 ) was added to the mixture.
g, 0.27
mol) was added dropwise to this solution and the temperature was maintained at 60-65°C. The reaction mixture was k |
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