| Chemical Properties | Back Directory | [Boiling point ]
1593.2±65.0 °C(predicted) | [density ]
1.284±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
4.01±0.10(predicted) | [Sequence]
cyclo{Trp-Asp-Ile-Asn-Asn-Asn-βAla} |
| Hazard Information | Back Directory | [Uses]
SPSB2-iNOS inhibitory cyclic peptide-2 (Compound CP2) is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 21 nM. SPSB2-iNOS inhibitory cyclic peptide-2 is reduction-resistant and oxidatively stable[1]. | [References]
[1] Yap BK, et al., Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction. FEBS Lett. 2016 Mar;590(6):696-704. DOI:10.1002/1873-3468.12115 |
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Fuan Bio
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15002819872 |
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fuanbio.com / www.fuanbio.com |
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