| Identification | Back Directory | [Name]
APS-2-79 | [CAS]
2002381-25-9 | [Synonyms]
6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine
4-Quinazolinamine, 6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)- | [Molecular Formula]
C23H21N3O3 | [MOL File]
2002381-25-9.mol | [Molecular Weight]
387.43 |
| Chemical Properties | Back Directory | [Boiling point ]
528.6±50.0 °C(Predicted) | [density ]
1.246±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
5.58±0.30(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
APS-2-79 is a modulator of KSR-dependent MAPK signaling, antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation as well as the activation of KSR-bound MEK (mitogen-activated protein kinase). | [IC 50]
KSR2: 120 nM (IC50); MEK1 |
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| Company Name: |
ChemShuttle, Inc.
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| Tel: |
0150-83588313-811 18800520310 |
| Website: |
www.jiehuapharma.com/ |
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