| Identification | Back Directory | [Name]
PD1 Inhbitor, Aurigene Cmpd 16 | [CAS]
2005454-12-4 | [Synonyms]
PD1 Inhbitor, Aurigene Cmpd 16
PD1 PDL1 IN 1,PD-1-PDL1-IN 1,PD1PDL1IN 1 | [Molecular Formula]
C14H23N7O6 | [MDL Number]
MFCD30747874 | [MOL File]
2005454-12-4.mol | [Molecular Weight]
385.38 |
| Hazard Information | Back Directory | [Description]
PD1-PDL1-IN 1 is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator[1]. PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is a receptor of the CD28 superfamily that negatively regulates T cell antigen receptor signalling by interacting with the specific ligands. PD-1 is suggested to play significant role in the maintenance of self-tolerance[1]. | [Uses]
PD1-PDL1-IN 1 (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator[1]. | [References]
[1] Pottayil Govindan Nair Sasikumar , et al. 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators. WO2016142886A2. |
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