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201849-55-0

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201849-55-0 Structure

201849-55-0 Structure
IdentificationBack Directory
[Name]

BOC-GLN-ALA-ARG-AMC HCL
[CAS]

201849-55-0
[Synonyms]

BOC-GLN-ALA-ARG-AMC HCL
Boc-Gln-Ala-Arg-AMC hydrochloride
[Molecular Formula]

C29H43ClN8O8
[MDL Number]

MFCD00237552
[MOL File]

201849-55-0.mol
[Molecular Weight]

667.16
Chemical PropertiesBack Directory
[storage temp. ]

-15°C
Hazard InformationBack Directory
[Uses]

Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC hydrochloride can also be used for measuring the proteolytic activity of TMPRSS2[1][2].
[References]

[1] Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292. DOI:10.1016/j.pan.2019.12.020
[2] Ko CJ, et al. Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis. Oncogene. 2020 Sep;39(37):5950-5963. DOI:10.1038/s41388-020-01413-w
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