| Identification | More | [Name]
N-Boc-Ethylenediamine | [CAS]
57260-73-8 | [Synonyms]
1-BOC-AMINO-1,2-ETHANEDIAMINE
1-BOC-ETHYLENEDIAMINE
(2-AMINO-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER
AKOS 91563
BOC-DIAMINOETHANE
BOC-EDA
BOC-NH-(CH2)2-NH2
BUTTPARK 27\08-29
N-1-T-BUTOXYCARBONYL-1,2-DIAMINOETHANE
N-1-T-BUTOXYCARBONYL-1,2-ETHYLENEDIAMINE
N-(2-AMINOETHYL)CARBAMIC ACID TERT-BUTYL ESTER
N-(2-AMINOETHYL)-N-BOC-AMINE
N-BOC-1,2-DIAMINOETHANE
N-BOC-DIAMINOETHANE
N-BOC-ETHYLENEDIAMINE
N-(T-BOC)ETHYLENEDIAMINE
N-TERT-BOC-ETHYLENEDIAMINE
N-(TERT-BUTOXYCARBONYL)-1,2-DIAMINOETHANE
N-(TERT-BUTOXYCARBONYL)-1,2-ETHYLENEDIAMINE
N-TERT-BUTOXYCARBONYL-ETHYLENEDIAMINE | [EINECS(EC#)]
611-490-6 | [Molecular Formula]
C7H16N2O2 | [MDL Number]
MFCD00191871 | [Molecular Weight]
160.21 | [MOL File]
57260-73-8.mol |
| Questions And Answer | Back Directory | [Synthesis]
Under vigorous stirring at 0°C, Boc₂O (25.0 mM) (100 mL) was dissolved in 100 mL of dichloromethane, and then slowly added dropwise over 3 h to a dichloromethane solution (100 mL) of ethylenediamine (150 mM). The resulting reaction mixture was stirred at room temperature for 16 h. After the reaction was complete, the solvent was evaporated to dryness, and the resulting residue was dissolved in 60 mL of sodium carbonate aqueous solution. The residue was extracted with dichloromethane (2 × 60 mL), the organic layer was dried on anhydrous Na₂SO₄, the desiccant was removed by filtration, and the solvent was evaporated from the resulting filtrate under reduced pressure to obtain the target product molecule N-Boc-Ethylenediamine.
 Figure: Synthetic route of N-Boc-Ethylenediamine |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless to very light yellow oily liquid | [Boiling point ]
72-80 °C0.1 mm Hg(lit.)
| [density ]
1.012 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.458(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Refrigerator (+4°C) | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Oily Liquid | [pka]
12.40±0.46(Predicted) | [color ]
Clear colorless to very light yellow | [Specific Gravity]
1.012 | [Water Solubility ]
Miscible with methanol and chloroform. Slightly miscible with water. | [Sensitive ]
Air Sensitive | [Detection Methods]
GC MS NMR | [BRN ]
1932330 | [Exposure limits]
ACGIH: TWA 100 ppm
OSHA: TWA 100 ppm(300 mg/m3)
NIOSH: IDLH 1600 ppm; TWA 100 ppm(300 mg/m3); STEL 150 ppm(450 mg/m3) | [InChI]
1S/C7H16N2O2/c1-7(2,3)11-6(10)9-5-4-8/h4-5,8H2,1-3H3,(H,9,10) | [InChIKey]
AOCSUUGBCMTKJH-UHFFFAOYSA-N | [SMILES]
NCCNC(OC(C)(C)C)=O | [CAS DataBase Reference]
57260-73-8(CAS DataBase Reference) | [Storage Precautions]
Air sensitive;Store under inert gas |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H314 | [Precautionary statements ]
P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2735 8/PG 3
| [WGK Germany ]
3
| [F ]
10-34 | [Hazard Note ]
Corrosive/Air Sensitive | [REACH Registrations]
Active | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29241990 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to very light yellow oily liquid | [Uses]
N-Boc-ethylenediamine is used in the synthesis of Thyronamine derivatives and analogs. | [Uses]
suzuki reaction | [reaction suitability]
reagent type: cross-linking reagent | [IC 50]
Alkyl-Chain |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
|