| Identification | Back Directory | [Name]
-Bis-(4-fluorophenyl) methoxytropane hydrochloride | [CAS]
202646-03-5 | [Synonyms]
5&beta
12&beta
17&beta
3&alpha
20&beta
(1&beta
15&beta
-diol-d4
12&alpha
23&alpha
5R,6&beta
-triol-d3
-triol-d7
3-(6&beta
-OL-12-ONE
-cholanoate
11,17&alpha
N-[(3&alpha
N-[(7&alpha
-equillenin
[1S-(1&alpha
3-Oxo-7&beta
(R*),3&alpha
3-Oxo-7&alpha
-TETROL-6-ONE
23R,25-pentol
-ol-20-one-d4
-Methyl-5&beta
Ribavirin
-oxiran]-3-one
-ETHYL-2&alpha
-Amino-7&alpha
3-Oxo-12&alpha
-bromo-5&alpha
-Hydroxy-5&beta
-METHYL-2&alpha
-pregnan-11-one
4-Chloro-6&beta
-Acetoxy 6&beta
-Triol (16&beta
)-7-Oxo-3&alpha
-sulfato-5&beta
-Androsterone-d6
-Androsterone-d4
23R,25-pentol-d6
-ethynyl-14&beta
-Hydroxy-5&alpha
-Acetoxy-2&alpha
-Hydroxy-17&beta
dione Sodium Salt
-Androstan-3&beta
-Pregnane-3&alpha
-androstan-16-one
-Dihydro-17&alpha
-DIPHENYL-3&alpha
-Estradiol 3-&beta
Estriol 3,16&alpha
-OL-12-ONE ACETATE
-diol Diacetate-d3
-Dihydroxy-5&alpha
-OH Gibberellin A3
-diol-d5 3-O-&beta
-cholanoic Acid-d4
-Trihydroxy-5&alpha
-Dihydrocortisol-d6
-diol 3-Glucuronide
)-Dihydroxy-6&alpha
-Androstane-3&alpha
-Acetoxy Ganaxolone
-dihydroxy-17&alpha
-ethynyl-equillenin
-Dimethylene-3&beta
-Androstanedione-d6
-Hydroxy Exemestane
21-Dihydroxy-5&alpha
21-Trihydroxy-5&beta
-diol 17-Glucuronide
Methyl 3-Keto-7&alpha
-DIOL 12-METHYL ETHER
-Androst-5-enediol-d3
-chol-9(11)-enic Acid
-Estradiol-d3 17&beta
-Androsterone-d5 &beta
-Hydroxy Exemestane-d3
-Hydroxyisocholic Acid
-diol 3-Glucuronide-d5
)-Cholane-3,7,24-triol
-Tetrahydro Norgestrel
)-CHOLENIC ACID-3&alpha
-OL-12-ONE METHYL ESTER
Pregna-1,4-dien-11&beta
-diol 17-Glucuronide-d5
AHN 1-055 hydrochloride
)-Estr-1-ene-3,17-dione
-D-Glucuronide-O-acetate
-Hydroxydeoxycholic Acid
-Methylbenzyl) Saligenin
-Dihydroxycholanoic Acid
-Methyl epi-Testosterone
-Dihydro Progesterone-d8
)-Pregnane-3,20,21-triol
-Hydroxy Drospirenone-d4
-androst-2-ene-2-methanol
-androstano[2,3-c]furazan
-Estradiol Dimethyl Ether
-Phenylacetoxy Tropane-d5
)-Cholane-3,7,24-triol-d5
-Dimethylandrostane-3&beta
-Estradiol 4-Carboxymethyl
Morphine 3-Acetate 6-&beta
-dihydroxyandrostan-17-one
19-Nor-5-androstene-3&beta
-androstano[3,2-c]pyrazole
-Dihydro Equilin 3-Sulfate
-Hydroxydeoxycholic Acid-d5
-Dihydrocortisol 21-Acetate
2-Hydroxymethylene (5&alpha
-Trihydroxycoprostanic Acid
-Methyl epi-Testosterone-d5
-DIOL DIACETATE METHYL ESTER
3,7-Dimethoxyethane (3&alpha
)-13-Ethyl-gonane-3,17-dione
-dimethyleneandrostan-3&beta
)-Estr-5(10)-ene-3,17-diol-d3
-Hydroxy-5,6-trans-vitamin D2
-cholan-24-oate Disodium Salt
-dimethyleneandrostane-3&beta
)-3-(Acetyloxy)pregnan-20-one
-Estradiol-(O-methyl) 3-&beta
-Methyl-6-dehydrotestosterone
)-19-Norpregnane-3,17,21-triol
17-Methyl-androst-5-ene-3&beta
)-3-Deoxy-3-chlorogalanthamine
-methyl-1,4-androstadien-3-one
)-3,11-Dihydroxypregnan-20-one
-Trihydroxycoprostanic Acid-d3
-methyl-1-(nitromethyl)-5&alpha
-Tetrahydro Cortisone 3-Acetate
-OH Gibberellin A3 Methyl Ester
21-tetrol-3-one 17,21-Diacetate
17-(3-Hydroxy-1-propynyl)-6&beta
)-16,17-Dihydroxyestr-4-en-3-one
-Methyl-6-dehydrotestosterone-d5
-Estradiol-d3 17-Acetate 3-&beta
22E)-Stigmasta-5,22-dien-3-ol-d6
19-Cycloandrostane-3,17-dione-d2
-Hydroxy-17-methyl-4-oxa-5&alpha
17-(3-Hydroxypropyl-13C3)-6&beta
-Carboxy-17-desoxy Dexamethasone
-methyl-1,4-androstadien-3-one-d3
20S)-Pregnane-3,20-diol Diacetate
-Hydroxy Exemestane-d3 17-O-&beta
-CHOLESTANE-B-HOMO-7-OXA-24&alpha
-OL-12-ONE 3-BENZOATE METHYL ESTER
)-CHOLENIC ACID-12-METHOXY-3&alpha
-Estradiol 3-O-Sulfate Sodium Salt
)-1,3-Dihydroxy-cholan-24-oic Acid
)-Allopregnanolone p-Nitrobenzoate
-Hydroxyisocholic Acid Methyl Ester
-methylandrost-4-eno[3,2-c]pyrazole
-DIOL METHYL ESTER, 12-METHYL ETHER
-androst-2-ene-2-methanol 7-Acetate
-Diacetate 2,3,4-Tri-O-acetyl-&beta
-D-Arabinofuranosyluracil-2-C-methyl
-Hydroxy-3-methoxy-17-methyl-5&alpha
-Estradiol-d5 Cyclic Ethylene Acetal
-Estradiol 17-Sulfate Potassium Salt
-4,5-Dihydro Prednisolone 21-Acetate
-Dihydrocortisone Acetate 21-Acetate
-Androsterone Sulfate Sodium Salt-d5
)-6-Hydroxy-3-oxo-cholan-24-oic Acid
3-O-Acetyl 5,14-Androstadiene-3&beta
17-(3-Hydroxy-1-propynyl-13C3)-6&beta
)-3,7,22-Trihydroxycholan-24-oic Acid
21R)-20-Acetate Pregnane-3,20-diol-d5
-Estradiol 3-O-Sulfate-d3 Sodium Salt
17-(Ethoxymethyl) Androst-5-ene-3&beta
-Androst-5-enediol 3-(p-Nitrobenzoate)
-Deoxycholic Acid Methyl Ester 3&alpha
)-3,7-Dihydroxy-24norcholane-23-nitrile
-Estradiol 17-Sulfate Potassium Salt-d3
)-2,3-Epoxy-androst-16-en-17-ol Acetate
-Acetyl-estradiol 3-(Tri-O-acetyl-&beta
-androst-2-ene-2-carboxaldehyde Acetate
)-3,5-Diaminocyclohexanecarboxylic Acid
-Estradiol 17-(2,3,4-Tri-O-acetyl-&beta
)-13-Ethyl-18,19-dinorpregnane-3,17-diol
)-3,18,21-Trihydroxypregnane-11,20-dione
-Hydroxy Medroxy Progesterone 17-Acetate
)-17-(Benzoyloxy)-4-oxaandrost-5-en-3-one
)-3,7,12-Tris(ethoxymethoxy)-cholan-24-ol
)-3,7,12-Tris(ethoxymethoxy)-cholan-24-al
-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
-D-glucuronide Methyl Ester) Ammonium Salt
-Petromyzonol 3,7,12-Triethoxymethyl Ether
-Acetyl-estradiol-d3 3-(Tri-O-acetyl-&beta
)-17-(Benzoyloxy)-4-oxaestr-5(10)-en-3-one
-D-Ribofuranosyl-3-aminocarbonyl Guandinine
)-2,17-Dimethyl-androst-1-ene-3,16,17-triol
)-3-[(4-Nitrobenzoyl)oxy]androst-5-en-17-one
24E)-3,7-Dihydroxy-cholest-24-en-26-oic Acid
-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C
-D-Glucuronide 2,3,4-Triacetate Methyl Ester
-dihydroxy-3-oxo-4-cholenoic Acid Sodium Salt
)-3,11,17,21-Tetrahydroxy-20-oxopregnan-18-al
-D-glucopyranoside 2,3-Diacetate Methyl Ester
-Hydroxy-7,17-dimethylandrosta-4,6-dien-3-one
)-7-Hydroxy-3,24-dioxochol-4-en-24-yl]glycine
24E)-3,12-Dihydroxy-cholest-24-en-26-oic Acid
-Glucosyl)glycerol (Mixture of Diastereomers)
)-13-Ethyl-17-hydroxy-18,19-dinorpregnan-3-one
)-Tetrahydro 11-Deoxycorticosterone 21-Acetate
-cholestan-26-oic Acid Methyl Ester Triacetate
-O-tert-Butyldimethylsilyl Tetrahydro Cortisone
)-5,17-Dihydroxy-6-methylpregnane-3,20-dione-d3
-Dihydrocortisol 21-O-(1-Ethoxy Ethyl) Ether-d6
-dihydroxy-3-oxo-4-cholenoic-d4 Sodium Salt Acid
)-13-Ethyl-3-methoxy-gona-2,5(10),15-trien-17-ol
)-3,17-Bis(ethoxymethoxy)-estra-1,3,5(10)-triene
Epiestriol 16 (1, 3, 5(10)-Estratrien-3, 16&beta
-D-Ribofuranosyl-3-iminohydroxymethyl Guandinine
-Hydroxy-1-(2-thienyl)-3-dimethylaminopropane-d6
)-11,17-Dihydroxy-17-methylandrost-4-en-3-one-d3
)-17,20:20,21-Bis[methylenebis(oxy)]pregnan-3-ol
24E)-3,7,12-Trihydroxy-cholest-24-en-26-oic Acid
-Estradiol 3-Sulfate 17-(2,3,4-Tri-O-acetyl-&beta
)-6-Hydroxy-3-oxo-cholan-24-oic Acid Methyl Ester
)-17,20:20,21-Bis[methylenebis(oxy)]pregnan-3-one
-Estradiol 3-O-Benzyl 17-(2,3,4-Tri-O-acetyl-&beta
)-13-Ethyl-3-methoxygona-1,3,5(10),8-tetraen-17-ol
)-7,12-Dihydroxy-3,24-dioxochol-4-en-24-yl]glycine
-Hydroxy Exemestane 17-O-[2,3,4-Tri-O-acetyl-&beta
-Bis-(4-fluorophenyl) methoxytropane hydrochloride
-Epoxy-16(17)-dehydrocorticosterone 11,21-Diacetate | [Molecular Formula]
C21H24ClF2NO | [MDL Number]
MFCD00671778 | [MOL File]
202646-03-5.mol | [Molecular Weight]
379.871 |
| Hazard Information | Back Directory | [Description]
Potent inhibitor of dopamine uptake and transport (Ki= 18 nM). | [Uses]
3α-Bis-(4-fluorophenyl) Methoxytropane Hydrochloride is a potent inhibitor of dopamine uptake and transport. | [in vivo]
AHN 1-055 (5 mg/kg; i.v.) inhibits the uptaking of brain dopamine with an IC50 of 311.8 ng/ml in vivo[1].
AHN 1-055 (10 mg/kg; i.v.) exhibits Cmax of 1.48 mg/L and terminal elimination half-lives of 7.69 h due to 1.8L/h/kg plasma clearance combined with 18.7 L/kg volumes of distribution[1].
| Animal Model: | Adult male Sprague Dawley rats (250-275 g)[1] | | Dosage: | 5?mg/kg (Pharmacokinetic Analysis) | | Administration: | I.v. administration | | Result: | Cmax (1.48 mg/L); T1/2 (7.69 h). |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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