| Identification | Back Directory | [Name]
N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide | [CAS]
2042365-85-3 | [Synonyms]
Kras4B G12D-IN-1
N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide | [Molecular Formula]
C16H21ClN2O4S | [MOL File]
2042365-85-3.mol | [Molecular Weight]
372.87 |
| Chemical Properties | Back Directory | [Boiling point ]
558.0±60.0 °C(Predicted) | [density ]
1.287±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
10.42±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Kras4B G12D-IN-1 is a Kras4B G12D inhibitor with anticancer effects. Kras4B G12D-IN-1 decreases Kras protein expression in mouse embryonic fibroblasts (MEF) expressing Kras4B G12D (WO2016179558A1, Comp 994566)[1]. | [IC 50]
KRas G12D | [References]
[1] Frank Mccormick, et al. K-ras modulators. WO2016179558A . |
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