ChemicalBook--->CAS DataBase List--->205252-59-1

205252-59-1

Request For Quotation
205252-59-1 Structure

205252-59-1 Structure
IdentificationBack Directory
[Name]

UAB 30
[CAS]

205252-59-1
[Synonyms]

UAB 30
(all-E)-UAB30
2,4,6-Octatrienoic acid, 8-(3,4-dihydro-1(2H)-naphthalenylidene)-3,7-dimethyl-, (2E,4E,6E,8E)-
[Molecular Formula]

C20H22O2
[MDL Number]

MFCD11840706
[MOL File]

205252-59-1.mol
[Molecular Weight]

294.39
Chemical PropertiesBack Directory
[Melting point ]

192-197 °C
[Boiling point ]

506.0±29.0 °C(Predicted)
[density ]

1.129±0.06 g/cm3(Predicted)
[pka]

4.71±0.33(Predicted)
Hazard InformationBack Directory
[Uses]

(all-E)-UAB30 (UAB30) is an retinoid X receptor (RXR) selective agonist.(all-E)-UAB30 shows anti-proliferation activity for MyLa, HuT 78, and HH cells with the IC50 of 34.7, 5.1, and 22.4 μM respectively[1][2].
[References]

[1] Adele P. Williams, et al. UAB30, A Novel Rexinoid Agonist, Decreases Stemness In Group 3 Medulloblastoma Human Cell Line Xenografts. Transl Oncol. 2019 Oct;12(10):1364-1374.
[2] Chu-Fang Chou, et al. The Retinoid X Receptor Agonist, 9-cis UAB30, Inhibits Cutaneous T-cell Lymphoma Proliferation Through the SKP2-p27kip1 Axis. J Dermatol Sci. 2018 Jun; 90(3): 343–356.
205252-59-1 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Company Name: Biorbyt Ltd.  
Tel: +44 (0)1223 859 353
Website: http://www.biorbyt.com
Tags:205252-59-1 Related Product Information