| Identification | Back Directory | [Name]
3'-(O-METHYL)CYTIDINE | [CAS]
20594-00-7 | [Synonyms]
3'-OMe-Cytidine
3'-(O-METHYL)CYTIDINE
Cytidine, 3'-O-methyl-
3'-(O-METHYL)CYTIDINE
3'-(O-METHYL)CYTIDINE USP/EP/BP
4-amino-1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]pyrimidin-2-one | [Molecular Formula]
C10H15N3O5 | [MDL Number]
MFCD00057449 | [MOL File]
20594-00-7.mol | [Molecular Weight]
257.24 |
| Chemical Properties | Back Directory | [Boiling point ]
506.0±60.0 °C(Predicted) | [density ]
1.68±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
13.34±0.70(Predicted) | [color ]
White to off-white | [InChI]
InChI=1S/C10H15N3O5/c1-17-8-5(4-14)18-9(7(8)15)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1 | [InChIKey]
RZJCFLSPBDUNDH-ZOQUXTDFSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](O)[C@@H]1OC |
| Hazard Information | Back Directory | [Uses]
3′-O-Methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. | [Definition]
ChEBI: 3'-O-Methylcytidine is a pyrimidine nucleoside. | [References]
[1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308 |
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