| Identification | Back Directory | [Name]
3'-O-METHYLURIDINE | [CAS]
6038-59-1 | [Synonyms]
3’-OMe-U
3'-O-Me-Ur
3'-OMe-Uridine
3'-O-METHYLURIDINE
3'-O-METHYLURIDINE
Uridine, 3'-O-methyl-
4-[1-[(2-methylphenyl)methyl]benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine | [Molecular Formula]
C10H14N2O6 | [MDL Number]
MFCD00057380 | [MOL File]
6038-59-1.mol | [Molecular Weight]
258.23 |
| Chemical Properties | Back Directory | [Melting point ]
142-145 °C | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [pka]
9.39±0.10(Predicted) | [InChI]
InChI=1S/C10H14N2O6/c1-17-8-5(4-13)18-9(7(8)15)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1 | [InChIKey]
YKNATSNMFLEFRB-ZOQUXTDFSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](O)[C@@H]1OC |
| Hazard Information | Back Directory | [Uses]
3’-O-Methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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