| Identification | Back Directory | [Name]
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-3-[[5-[3-(4-morpholinyl)-5-(trifluoromethyl)-2-pyridinyl]-1,3,4-oxadiazol-2-yl]amino]-5-phenyl-, (3S)- | [CAS]
2070852-76-3 | [Synonyms]
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-3-[[5-[3-(4-morpholinyl)-5-(trifluoromethyl)-2-pyridinyl]-1,3,4-oxadiazol-2-yl]amino]-5-phenyl-, (3S)- | [Molecular Formula]
C27H22F3N7O3 | [MOL File]
2070852-76-3.mol | [Molecular Weight]
549.5 |
| Chemical Properties | Back Directory | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 50 mg/mL (90.99 mM; Need ultrasonic) | [form ]
Solid | [pka]
11.68±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Zelicapavir (RSV-IN-7) (example 253) is a RSV inhibitor (EC50: < 0.4 μΜ)[1]. | [References]
[1] Shook Brian C., et al. Preparation of benzodiazepine derivatives for use as RSV inhibitors. Patent. WO2017015449 A1.
[2] Rhodin MHJ, et al., EDP-938, a novel nucleoprotein inhibitor of respiratory syncytial virus, demonstrates potent antiviral activities in vitro and in a non-human primate model. PLoS Pathog. 2021 Mar 15;17(3):e1009428. |
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