| Identification | Back Directory | [Name]
ABBV-2737 | [CAS]
2093974-63-9 | [Synonyms]
ABBV-2737
1H-Pyrazolo[3,4-b]pyridine-6-carboxamide, 3-cyclobutyl-N-[(dimethylamino)sulfonyl]-1-(4-fluorophenyl)-4-(4-methoxy[1,4'-bipiperidin]-1'-yl)- | [Molecular Formula]
C30H40FN7O4S | [MOL File]
2093974-63-9.mol | [Molecular Weight]
613.75 |
| Hazard Information | Back Directory | [Uses]
GLPG2737 is a potent CFTR type 2 corrector, and GLPG2737 can be used in combination with a type 1 co-corrector in the study of cystic fibrosis[1]. | [References]
[1] Pizzonero M, et al. Discovery of GLPG2737, a Potent Type 2 Corrector of CFTR for the Treatment of Cystic Fibrosis in Combination with a Potentiator and a Type 1 Co-corrector. J Med Chem. 2024 Apr 11;67(7):5216-5232. DOI:10.1021/acs.jmedchem.3c01790 |
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