| Identification | Back Directory | [Name]
N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine | [CAS]
2095417-23-3 | [Synonyms]
N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine | [Molecular Formula]
C24H27N5O7 | [MDL Number]
MFCD30718398 | [MOL File]
2095417-23-3.mol | [Molecular Weight]
497.5 |
| Hazard Information | Back Directory | [Uses]
N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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