ChemicalBook--->CAS DataBase List--->2098497-24-4

2098497-24-4

2098497-24-4 Structure

2098497-24-4 Structure
IdentificationBack Directory
[Name]

Fmoc-D-homoArg(Et)2-OH·HCl
[CAS]

2098497-24-4
[Synonyms]

Fmoc-D-homoArg(Et)2-OH·HCl
Fmoc-d-homoarg(et)2-oh hydrochloride salt
Fmoc-D-Har(Et)2-OH/Fmoc-D-HomoArg(Et)2-OH.HCl(symmetrical)
(2R)-6-[[amino(diethylamino)methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
(2R)-6-[(E)-N',N''-diethylcarbamimidamido]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid hydrochloride
[Molecular Formula]

C26H35ClN4O4
[MDL Number]

MFCD28385803
[MOL File]

2098497-24-4.mol
[Molecular Weight]

503.04
Hazard InformationBack Directory
[Uses]

Fmoc-D-homoArg(Et)2-OH (hydrochloride) is a Fmoc-protected derivative of D-Homoarginine (HArg) that renders peptides and proteins resistant to proteolysis by trypsin. Fmoc-D-homoArg(Et)2-OH (hydrochloride) can be used as a cleavable ADC linker to synthesize antibody-drug conjugates (ADCs)[1].
[References]

[1] Zhu R, et al. An Efficient and Economical Method for the Preparation of Fmoc‐Argω, ω′(Boc) 2‐OH[J]. Chinese Journal of Chemistry, 2010, 28(8): 1508-1509.
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