| Identification | Back Directory | [Name]
Benzeneacetamide, N-[3-[(3,4-dihydro-2,4-dioxo-3-propylthieno[3,2-d]pyrimidin-1(2H)-yl)methyl]phenyl]- | [CAS]
2098776-03-3 | [Synonyms]
FEN1-IN-SC13
FEN1 inhibitor SC13
N-(3-((2,4-dioxo-3-propyl-3,4-dihydrothieno[3,2-d]pyrimidin-1(2H)-yl)methyl)phenyl)-2-phenylacetamide
Benzeneacetamide, N-[3-[(3,4-dihydro-2,4-dioxo-3-propylthieno[3,2-d]pyrimidin-1(2H)-yl)methyl]phenyl]- | [Molecular Formula]
C24H23N3O3S | [MOL File]
2098776-03-3.mol | [Molecular Weight]
433.52 |
| Chemical Properties | Back Directory | [density ]
1.325±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 62.5 mg/mL (144.17 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [pka]
14.86±0.70(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
FEN1-IN-SC13 is a potent DNA fragmentation endonuclease 1 (FEN1) inhibitor with antitumor activity. FEN1-IN-SC13 interferes with DNA replication and repair in vitro and in cells[1]. | [Biological Activity]
FEN1-IN-SC13 is a potent DNA fragmentation endonuclease 1 (FEN1) inhibitor (CN106692155A, SC13)[1]. | [in vivo]
FEN1-IN-SC13 (injection, a single dose for 40 days) combined with chemotherapy drugs inhibits the tumor growth in the xenografted tumor models[1].
| [storage]
Store at -20°C | [References]
[1]. Application of small-molecular inhibitor SC13 targeting to FEN1 and derivative of small-molecular inhibitor SC13 in preparing tumor treatment medicine. CN106692155A. |
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| Company Name: |
nanjing
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13376084917 13376082704 |
| Website: |
www.linye-e.com/ |
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