| Identification | Back Directory | [Name]
1,3-Dioxane-5-carboxylic acid, 2-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,3,5,6-tetrafluoro-4-sulfophenyl ester, cis- | [CAS]
2102021-49-6 | [Synonyms]
MDTF free acid
1,3-Dioxane-5-carboxylic acid, 2-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,3,5,6-tetrafluoro-4-sulfophenyl ester, cis- | [Molecular Formula]
C16H11F4NO9S | [MOL File]
2102021-49-6.mol | [Molecular Weight]
469.32 |
| Hazard Information | Back Directory | [Uses]
MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [References]
[1] Dovgan I, et, al. 2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation. Sci Rep. 2016 Aug 9;6:30835. DOI:10.1038/srep30835 |
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