| Identification | Back Directory | [Name]
N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 | [CAS]
2107273-30-1 | [Synonyms]
N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 | [Molecular Formula]
C49H68ClN3O12 | [MDL Number]
MFCD29079411 | [MOL File]
2107273-30-1.mol | [Molecular Weight]
926.54 |
| Hazard Information | Back Directory | [Description]
N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 is a cyanine labeled PEG linker with excitation/emmission maximum 649/667 nm containing a NHS ester group, which is an amine reactive group. Hydophilic PEG spacer increases solubility in aqueous media. This reagent can be utilized to produce Cyanine-labeled biomolecules for subsequent use such as in vivo research, and drug design related experiments. | [Uses]
N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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