| Identification | Back Directory | [Name]
Bis-(N,N'-PEG4-NHS ester)-Cy5 | [CAS]
2107273-48-1 | [Synonyms]
Bis-(N,N'-PEG4-NHS ester)-Cy5 | [Molecular Formula]
C55H73ClN4O16 | [MDL Number]
MFCD29918262 | [MOL File]
2107273-48-1.mol | [Molecular Weight]
1081.65 |
| Hazard Information | Back Directory | [Description]
Bis-(N,N'-NHS-PEG4)-Cy5 is a cyanine labeled PEG linker with excitation/emmission maximum 649/667 nm containing a NHS ester group, which is an amine reactive group. Hydophilic PEG spacer increases solubility in aqueous media. This reagent can be utilized to produce Cyanine-labeled biomolecules for subsequent use such as in vivo research, and drug design related experiments. | [Uses]
Bis-(N,N'-PEG4-NHS ester)-Cy5 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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