| Identification | More | [Name]
ISOXAZOLE-5-CARBOXYLIC ACID | [CAS]
21169-71-1 | [Synonyms]
AKOS PAO-1371
BUTTPARK 27\08-41
ISOXAZOLE-5-CARBOXYLIC ACID
TIMTEC-BB SBB004319
5-Isoxazolecarboxylic acid
Isoxazole-5-carboxylic acid 98%
Isoxazole-5-carboxylic acid ,98% | [Molecular Formula]
C4H3NO3 | [MDL Number]
MFCD00156151 | [Molecular Weight]
113.07 | [MOL File]
21169-71-1.mol |
| Chemical Properties | Back Directory | [Appearance]
slightly yellow powder | [Melting point ]
144-148 °C(lit.) | [Boiling point ]
211.74°C (rough estimate) | [density ]
1.5808 (rough estimate) | [refractive index ]
1.4543 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
Powder | [pka]
2.29±0.10(Predicted) | [color ]
Slightly yellow | [Water Solubility ]
Slightly soluble in water. | [Sensitive ]
Moisture Sensitive | [InChI]
InChI=1S/C4H3NO3/c6-4(7)3-1-2-5-8-3/h1-2H,(H,6,7) | [InChIKey]
MIIQJAUWHSUTIT-UHFFFAOYSA-N | [SMILES]
O1C(C(O)=O)=CC=N1 | [CAS DataBase Reference]
21169-71-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S25:Avoid contact with eyes .
S24:Avoid contact with skin .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Chemical Properties]
slightly yellow powder | [Uses]
Reaction conditions were found to allow the exclusive formation of isoxazole-5-carboxylic acid derivatives by conjugate addition, in acidic medium, of hydroxylamine to β-alkoxyvinyl trichloromethyl ketone in synthesis and reactivity of isoxazoles. Isoxazole-5-carboxylic acid participates in the Synthesis and evaluation of acylguanidine FXa inhibitors. 1, 1, 1-trichloro-4-methoxy-3-penten-2-one postulated in the preparation of isoxazole-5-carboxylic acid from trichloroacetyl chloride, ethyl vinyl ether and hydroxylamine is developed in a fully saturated nitrogen atom theerefore there is no possibility of conjugation with 4- substituents. | [General Description]
Isoxazole-5-carboxylic acid can be obtained via dehydration of 5-trichloromethylisoxazole. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
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| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
China Langchem Inc.
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| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
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